新生儿缺氧缺血性脑病并寒冷损伤综合征发病因素分析

Analysis of the pathogenesis of hypoxic ischemic encephalopathy and cold injury syndrome

目的探究新生儿缺氧缺血性脑病并寒冷损伤综合征发病因素,并制定预防和治疗措施。方法回顾性分析2010年1月～2017年12月本院收治的新生儿缺氧缺血性脑病并寒冷损伤综合征者为研究对象,开展针对性处理措施。结果经治疗后,治愈者14例,好转者1例,自动出院者1例。有效率为100.00%,病死率0.00%。症状消失时间为(9.08±7.21)d,住院天数为(10.23±7.02)d。和干预前相比,干预后体温,心率,临床症状评分以及血压均有所改善,差异具有统计学意义(P<0.05),脉搏数和干预前相比差异无统计学意义。结论窒息、早产、寒冷等为引起新生儿缺氧缺血性脑病并寒冷损伤综合征的发生因素,在围产期内,应对新生儿做好相关保健工作,加强保暖力度,以防止上述疾病发生。

Objective To explore the pathogenic factors of neonatal hypoxic ischemic encephalopathy and cold injury syndrome, and to develop prevention and treatment measures. Methods A retrospective analysis was conducted on the patients with hypoxic ischemic encephalopathy and cold injury syndrome treated in our hospital from January 2010 to December 2017. Results After treatment, 14 patients were cured, 1 case was improved and 1 patient was admitted. The effective rate was 100.00% and the fatality rate was 0.00%. The duration of symptoms was（9.08±7.21） d, and the length of hospitalization was（10.23±7.02）d. Compared with before intervention, the body temperature, heart rate, clinical symptom score and blood pressure were all improved after the intervention（P〈0.05）. The pulse number was not significantly different from that before intervention.Conclusion Asphyxia, premature birth, cold to cause the occurrence of neonatal hypoxic ischemic encephalopathy and cold injury syndrome factors,within the perinatal, handle related to neonatal care, strengthen to keep warm, to prevent the disease.