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格列苯脲联合二甲双胍强化治疗初诊2型糖尿病患者的临床效果 被引量:1

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摘要 目的探讨格列苯脲联合二甲双胍强化治疗初诊2型糖尿病患者的临床效果。方法将2016年6月至2017年10月收治的136例初诊2型糖尿病患者随机分为试验组和对照组,各68例。试验组予以格列苯脲联合二甲双胍治疗,对照组予以格列苯脲治疗,对比分析治疗前后两组餐后2 h血糖(2 h PG)、空腹血糖(FPG)、糖化血红蛋白(Hb A1C)及胰岛素抵抗指数(HOMA-IR)变化情况。结果治疗前,两组的2 h PG,FPG,Hb A1C及HOMA-IR水平比较,差异均无统计学意义(P>0.05)。治疗后,试验组的2 h PG,FPG,Hb A1C及HOMA-IR水平均明显低于对照组,差异均有统计学意义(P<0.05)。结论采用格列苯脲联合二甲双胍强化治疗初诊2型糖尿病患者,可有效控制患者的血糖水平,并能有效改善胰岛素抵抗现象,对改善患者的预后具有十分重要的临床意义。
作者 魏雪莲
出处 《医疗装备》 2018年第9期138-139,共2页 Medical Equipment
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