三黄止痒搽剂联合耳背静脉放血治疗轻度痤疮疗效观察

Observation on the Curative Effect of Sanhuang Antipruritic Liniment Combined with Posterior Auricular Vein Bloodletting Therapy in Treating Mild Acne

目的 ：观察三黄止痒搽剂联合耳背静脉放血治疗面部轻度痤疮的临床疗效及安全性。方法 ：将所有入选患者按照随机数字表法分为两组,每组各60例。治疗组给予三黄止痒搽剂联合耳背静脉放血治疗,对照组采用0.025%维A酸乳膏外涂治疗,疗程均为4周。结果：治疗结束时,治疗组临床总有效率86.76%,对照组56.30%,两组比较差异有统计学意义（P〈0.05）;治疗组的皮损积分较对照组有明显下降,差异有统计学意义（P〈0.05）;治疗组的不良反应发生率8.33%（5/60例）,而对照组38.33%（23/60例）,两组差异有统计学意义（P〈0.05）。结论 ：三黄止痒搽剂联合耳背静脉放血治疗面部轻度痤疮疗效确切且安全,易被患者接受。

Objective：To observe the clinical efficacy and safety of Sanhuang antipruritic liniment combined with posterior auricular vein bloodletting therapy in the treatment of mild acne vulgaris. Methods：The patients were randomly divided into the treatment group and control group. The treatment group was treated with Sanhuang antipruritic liniment combined with posterior auricular vein bloodletting therapy,while the control group was given cream containing 0.025% tretinoin. The course of treatment lasted for four weeks.Results：At the end of the treatment,the total clinical efficacy in the treatment group was 86.76%,while that in the control group was 56.3%,with statistical difference between two groups（P〈0.05）. The lesion score in the treatment group was significantly lower than that in the control group（P〈0.05）. The incidence of adverse events in the treatment group was 8.33%,while that in the control group was 38.33%,with statistical difference between two groups（P〈0.05）. Conclusion：Sanhuang antipruritic liniment combined with posterior auricular vein bloodletting therapy was a effective and safe treatment for mild acne,and it is easily accepted by the patients.