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重度牙周炎伴药物性牙龈肥大一例 被引量:4

Cyclosporin-related gingival enlargement in patient with severe chronic periodontitis: a case report
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摘要 药物性牙龈肥大是指长期应用某些药物引起牙龈的纤维性增生与体积增大,临床上与药物性牙龈肥大相关的三类常用药物包括抗癫痫药(如苯妥英钠)、免疫抑制剂(如环孢素)及钙离子通道阻滞剂(如硝苯地平)。严重的牙龈肥大可引起患者咀嚼困难,影响发音及面部美观,对患者身心健康造成严重影响。临床上可采用的治疗方法包括严格的口腔卫生措施、牙周基础治疗、停药或换药、抗菌药物治疗以及手术治疗。有病例报道显示完善的牙周基础治疗可以缓解牙龈的炎症,从而减轻或消除牙龈肥大增生。中山大学光华口腔医学院牙周病科收治1例环孢素相关的药物性牙龈肥大病例,通过牙周基础治疗和严格的自我菌斑控制,取得了良好的疗效,现报道如下。
作者 朱文俊 谭媛元 付云 Zhu Wenjun, Tan Yuanyuan, Fu Yun(1Department of Periodontology, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University & Guangdong Provincial Key Laboratory of Stomatology, Guangzhou 510055, China ;2Present address: Department of Dentistry, People's Hospital of Longgang District, Shenzhen Guangdong 518172, Chin)
出处 《中华口腔医学杂志》 CAS CSCD 北大核心 2018年第5期355-358,共4页 Chinese Journal of Stomatology
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