尘肺病右心室功能的超声心动图评价

Evaluation of the right ventricular function in patients with pneumoconiosis by echocardiography

目的评价尘肺病患者的右心室功能，对尘肺病的临床诊疗量化评价提供依据。方法选取石家庄市职业病防治院2015年5月至2016年5月43例连续住院的尘肺病患者，其中尘肺壹期组16例，尘肺贰期组14例，尘肺叁期组13例，另选取正常对照组16例。进行超声心动图检查，记录相关测量数据：右心室横径（RVD）、三尖瓣环收缩期位移（TAPSE）、右心室做功指数（Tei）。结果除壹期组Tei指数与对照组差异无统计学意义（P〉0．05），壹期组TAPSE与贰期组差异无统计学意义（P〉0．05）外，其余各组Tei指数、TAPSE的差异均有统计学意义（P〈0．05），右心室Tei指数与TAPSE呈负相关（r=-0．547，P〈0．05）。结论右心室Tei指数与TAPSE联合应用能早期量化评估尘肺病患者的右心室功能。

Objective To investigate right ventricular function in patients with pneumoconiosis, and to provide a basis for quantitative diagnosis and treatment of pneumoconiosis in clinical practice. Methods A total of 43 patients with pneumoconiosis who were hospitalized consecutively in Shijiazhuang Prevention and Treatment Center for Occupational Diseases from May 2015 to May 2016 were enrolled, and according to the stage of pneumoconiosis, they were divided into stage I group with 16 patients, stage II group with 14 patients, and stage III group with 13 patients. A total of 16 healthy subjects were enrolled as control group. Echocardiography was performed and the relevant parameters were recorded, i.e., right ventricular transverse diameter （RYTD）, tricuspid annular plane systolic excursion （TAPSE）, and right ventricular myocardial performance index（Tei index）. Results There were significant differences in Tei index and TAPSE between all groups （P 〈0.05 ） except between the stage I group and the control group in terms of Tei index （P〉0.05） and between the stage I group and the stage II group in terms of TAPSE （P〉0.05）. Right ventricular Tei index was negatively correlated with TAPSE （r=-0.547 ,P〈0.05）. Conclusion A combination of right ventricular Tel index and TAPSE can be used for early quantitative evaluation of fight ventricular function in patients with pneumoconiosis.