开封市2015年儿童疑似预防接种异常反应监测结果分析

Suspected adverse events following immunization among children in Kaifeng city:monitoring data analysis,2015

目的分析河南省开封市2015年儿童疑似预防接种异常反应(AEFI)的的流行病学特点。方法收集河南省开封市2015年度报告的儿童AEFI个案数据,应用描述性统计对流行病学进行分析,总结儿童AEFI发生特征。结果 2015年河南开封市AEFI地区分布以顺河回族区(19.50%)、尉氏县(17.03%)、金明区(13.00%)为主,个案报告县、乡覆盖率分别为100.00%、97.97%;AEFI年龄分布以<1岁(58.51%)为主,其次为1~2岁(29.10%);AEFI病例报告时间以8月份(23.22%)为主;AEFI接种疫苗以乙脑疫苗(减毒)所占比例最高(23.22%);AEFI类型以一般反应所占比例最高(95.67%);临床症状以发热(80.19%)、局部红肿(21.05%)、哭闹(10.53%)为主;AEFI临床损伤以一般反应症状所占比例(95.67%)最高。结论 2015年开封市儿童AEFI主要分布于顺河回族区,以<1岁儿童为主,多发生于夏秋季节,AEFI反应类型以一般反应为主。

Objective To analyze epidemiological characteristics of suspected adverse events following immunization（AEFI） among children in Kaifeng municipality（Kaifeng） of Henan province in 2015. Methods The data on children with AEFI reported in Kaifeng during 2015 were collected. Descriptive epidemiological methods were adopted to analyze the incidents of AEFI. Results The reported cases of AEFI distributed in almost all the administration regions（100.00% for county level and 97.97% for township level） in the year and more cases were reported in Shunhe Hui ethnic district（19.50%）,Weishi county（17.03%）, and Jinming district（13%）. The majority of the reported AEFI cases were small children less than one year old（58.51%） and at the ages one to two years（29.10%）. More AEFI cases were reported in August（23.22%） of the year. The proportion of the cases related to vaccination of attenuated Japanese encephalitis vaccine was the highest（23.22%）.Nearly all the reported cases（95.67%） were categorized as general type of AEFI, with main clinical symptoms of fever（80.19%）, local red and swollen（21.05%）, and crying（10.53%）. Conclusion In Kaifeng municipality during 2105, the reported cases of AEFI were mainly small children less one year old; more cases were reported in summer and autumn season and general reaction was the major type of AEFI reported.