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Slit/Robo信号通路在肿瘤发生发展中的作用 被引量:2

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摘要 分泌型糖蛋白Slit通过结合跨膜受体Roundabout(Robo)发挥生物学活性。Slit/Robo信号通路除了在神经系统中发挥轴突导向作用外,还参与了肿瘤的发生、发展。本文侧重于从Slit/Robo结构、Slit/Robo信号在肿瘤中的表达,Slit/Robo信号对肿瘤新生血管、肿瘤细胞生长及迁移的作用等方面进行综述,为深入研究Slit/Robo信号通路与肿瘤的关系提供参考依据。
出处 《癌症进展》 2018年第4期417-420,共4页 Oncology Progress
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