甲状旁腺激素检测对脉管炎的诊断价值

Diagnostic value of parathyroid hormone detection in vasculitis

目的探讨甲状旁腺激素检测对脉管炎疾病的诊断价值。方法选取100例诊断为心血管系统疾病并伴有脉管炎的患者为研究组,选择同时段体检健康的100例志愿者为对照组。定期测定两组入院时和入院后甲状旁腺激素、降钙素原、C-反应蛋白、血常规、血磷、血钙及肝肾功能等指标,比较上述指标在两之间,研究组内不同病程的患者之间的变化差异。结果研究组患者血液中甲状旁腺激素、C-反应蛋白、降钙素原及血磷和血钙的水平均高于对照组,差异均有统计学意义(P<0.05);研究组患者随着病情的加重,以上指标均显著增加,差异均有统计学意义(P<0.05)。结论甲状旁腺激素与脉管炎的发生及病程存在相关性,对脉管炎疾病的早期诊断和治疗具有指导意义,可有效评估脉管炎患者预后。

Objective To investigate the early diagnostic and therapeutic value of parathyroid hormone in the diagnosis and treatment of vasculitis. Methods A total of 100 patients with cardiovascular disease and vasculitis were selected as the study group, and 100 healthy people checked by physical examination were selected as the control group. The indexes of parathyroid hormone, procalcitonin C-reactive protein, blood routine, blood phosphorus, blood calcium and liver and kidney function were examinated regularly before and after hospitalized. The above indexes were compared between the two groups and different courses of disease. Results The levels of parathyroid hormone, C-reactive protein, procalcitonin, serum phosphorus and calcium in the study group were higher than those in the control group,the differences were significant（P 〈0. 05 ）. The above indexes increased significantly with the aggravation of the patients in the study group, and the differences were significant （P〈 0.05 ）. Conclusions Parathyroid hormone is correlated with the occurrence and course of vasculitis, which is of great significance to the early diagnosis and treatment of vasculitis, and can evaluate the prognosis of patients with vasculitis effectively.