子午流注针刺疗法治疗重症COPD患者胃肠道功能紊乱的疗效观察

Efficacy of Ziwuliuzhu acupuncture therapy in the treatment of gastrointestinal dysfunction inpatients with severe COPD

[目的]观察子午流注针刺疗法治疗重症慢性阻塞性肺疾病(COPD)患者胃肠道功能紊乱的疗效。[方法]以45例重症COPD患者为研究对象,随机分为3组,对照组采用常规治疗和肠内营养治疗,辰时观察组采用于辰时行针刺治疗结合常规治疗和肠内营养治疗,未时观察组采用于未时行针刺治疗结合常规治疗和肠内营养治疗。以患者治疗前后的体重指数、胃肠道并发症发生率和住院时间作为观察指标,以期较为客观地评价针刺干预重症COPD患者胃肠功能紊乱的临床疗效及探讨不同时辰的施针效应。[结果]3组的治疗方法均能改善患者的营养状况(P<0.05,P<0.01),且辰时观察组效果最佳,其次是未时观察组、对照组。治疗后,未时观察组、辰时观察组的胃肠道并发症发生率均低于对照组(P<0.05,P<0.01),而辰时观察组的胃肠道并发症发生率明显低于未时观察组(P<0.05)。与对照组比较,辰时观察组、未时观察组住院时间明显减少,差异均有显著统计学意义(P<0.01);与未时观察组比较,辰时观察组住院时间较少,差异有统计学意义(P<0.05)。[结论]子午流注针刺疗法能有效治疗重症COPD胃肠道功能紊乱,为临床针刺治疗重症COPD患者胃肠功能紊乱提供依据。

[Objective]To observe the effect of Ziwuliuzhu acupuncture therapy on gastrointestinal dysfunction in patients with severe chronic obstructive pulmonary disease（COPD）.[Methods]Fifty-fivepatients with severe COPD were randomly divided into 3 groups.The control group was treated with conventional therapy and enteral nutrition.The Chenshi observation group used acupuncture at the time of Chenshi（the period of the day from 11 p.m.to 1 a.m.）combined with conventional treatment and enteral nutrition.The Weishi observation group used acupuncture at the time of Weishi（the period of the day from 1 p.m.to 3 p.m.）combined with conventional treatment and enteral nutrition.The body mass index before and after treatment,the incidence of gastrointestinal complications and length of stay were taken as observation indexes,in order to objectively evaluate the clinical efficacy of acupuncture intervention on gastrointestinal dysfunction in patients with severe COPD and to explore the effect of acupuncture at different times.[Results]The treatment methods of the three groups all improved the nutritional status of patients（P〈0.05,P〈0.01）.The Chenshi observation group had the best efficacy,followed by the Weishi observation group andthe control group.After treatment,the incidence of gastrointestinal complications in the Weishi and Chenshi observation group were lower than that in the control group（P〈0.05,P〈0.01）,and the incidence of gastrointestinal complications in the Chenshi observation group was lower than that in the Weishi observation group（P〈0.05）.Compared with the control group,the lengths of stay in the Chenshi and Weishi observation group were significantly decreased（P〈0.01）.And the lengths of stay in the Chenshi observation group was less than that in Weishi observation group（P〈0.05）.[Conclusion]Ziwuliuzhu acupuncture therapy can effectively treat gastrointestinal dysfunction in patients with severe COPD,and provide basis for clinical acupuncture treatment of gastrointestinal dysfunction inpatients with severe COPD.