支气管哮喘气道重塑的研究进展

Progress of airway remodeling in bronchial asthma

除气道炎症和气道高反应性外，气道重塑也是支气管哮喘（简称哮喘）的重要发病机制。气道重塑是哮喘的非特异性炎症改变，可引起持续性气流受限、肺功能下降等，与哮喘的严重程度、疾病进展以及预后密切相关。近年来对气道重塑有了新的探索和发现，本文将对其部分研究进展作一综述。

Airway remodeling is a key pathogenesis of brochial asthma（asthma） in addition to airway inflammation and airway hyperresponsiveness. Airway remodeling is a non-specific inflammatory change of asthma, which can result in persistent airflow limitation and lung function decline. Moreover, airway remodeling is closely related to the severity of asthma, disease progression and prognosis. In recent years, new exploration and discovery have been made for airway remodeling. This article will review some of its research progress.