尘肺患者疾病负担病例对照研究

Case-control study of the burden of pneumoconiosis

目的分析尘肺患者疾病负担现状及其影响因素,为采取有针对性的干预措施提供科学依据。方法采用病例对照研究,伤残调整寿命年计算和多因素回归分析方法 ,研究尘肺患者的直接经济负担、间接经济负担、伤残调整寿命年(disability adjusted life years,DALY)损失及其影响因素。结果尘肺患者人均直接经济损失为6 363.28元;尘肺患者人均间接经济损失为67 207.05元。241例尘肺患者DALY损失平均值为6.22个健康年。年龄、工龄、并发症、尘肺分期为尘肺患者DALY损失的影响因素(均有P<0.05)。结论尘肺患者存在较大的直接经济和间接疾病负担;影响DALY损失的因素可能为年龄、工龄、并发症、尘肺分期。

Objective To investigate the burden of pneumoconiosis and its influencing factors, and to provide scientific basis for developing specific intervention measures. Methods A case-control study was conducted to analyze patients＇ direct and indirect economic burdens of pneumoconiosis and its influencing factors by using disability adjusted life year （DALY） and multiple factor regression analysis. Results The direct and indirect economic loss percapita attributed to pneumoconiosis were 6 363.28 yuan and 67 207.05 yuan respectively. Patients＇ average DALY loss due to pneumoconiosis was 6. 22 years. The main influencing factors of pneumoconiosis patients＇ DALY were age, working years, complications, and disability levels （all P 〈 0. 05). Conclusions The direct and indirect economic burdens, DALY loss due to pneumoconiosis were great. Age, working years, complications and disability levels were major factors that influence the DALY of patients with pneumoconiosis.