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小剂量利妥昔单抗用于治疗难治性血小板减少症的临床效果 被引量:3

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摘要 目的:分析小剂量利妥昔单抗用于治疗难治性血小板减少症的临床效果。方法:随机选择2014年12月至2016年11月在阳江市人民医院接受治疗的难治性血小板减少症患者62例,分为对照组(30例)及观察组(32例),给予对照组常规治疗,而观察组在对照组基础上结合小剂量利妥昔单抗(100 mg,每周1次,共治疗4次)进行治疗。比较两组患者疗效。结果:与对照组比较,观察组患者外周血血小板计数升高较为明显,总反应率达到78.13%,而完全反应(CR)率达到53.13%,组间比较,差异具有统计学意义(P<0.05)。结论:为治疗难治性血小板减少症患者,开展常规治疗的基础上结合小剂量利妥昔单抗,疗效明显,可有效改善临床出血的情况,且安全性高。
机构地区 阳江市人民医院
出处 《深圳中西医结合杂志》 2018年第4期105-107,共3页 Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
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