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调控容量负荷对高血压治疗的疗效观察 被引量:1

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摘要 目的研究调控容量负荷对高血压治疗的临床疗效。方法高血压患者50例依照治疗方案不同分组,各25例。对照组使用厄贝沙坦、美托洛尔缓释片治疗;容量负荷调控组严格限制钠盐,在对照组基础上加用氢氯噻嗪三联降压药治疗。比较两组容量负荷变化与临床疗效。结果容量负荷调控组治疗总有效率高于对照组(P<0.05);收缩压、舒张压低于对照组(P<0.05);体重、细胞外液、总体液水平低于对照组(P<0.05);血肌酐、尿素氮略高于对照组(P>0.05);治疗后两组血浆肾素活性、血管紧张素Ⅱ差异无统计学意义(P>0.05)。结论注重容量负荷调整与临床疗效有显著的相关性。
机构地区 湖南省人民医院
出处 《中国地方病防治》 CAS 2018年第2期233-234,共2页 Chinese Journal of Control of Endemic Diseases
基金 湖南省自然科学基金资助项目(13JJ5020)
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