鸡人工感染弓形虫病的组织学病理变化

Histopatholoqical Changes of Chickens with Artificially Infected Toxoplasmosis

为研究鸡弓形虫病,人工给鸡经口感染弓形虫虫卵,取眼观症状变化明显的脾脏,肝脏,肾脏做石蜡切片,HE染色镜检观察其病理学变化。观察到脾脏主要发生白细胞变性坏死,红髓中可见坏死灶。充血出血,脾窦含血量增多,水肿。肝脏组织内发生局部炎症,有浆液性物质浸润,肝脏间隙可见大量嗜酸性细胞,充血出血。有核细胞内发现包囊。肾脏发生变性,坏死,充血出血,水肿,肾脏间隙可见大量嗜酸性细胞等。

In order to study chicken toxoplasmosis,chickens were orally and artificially infected with toxoplasma eggs.The spleen,liver and kidney with obvious changes in the eye were paraffin-embedded,and the pathological changes were observed by HE staining.The main occurrence of leukocyte degeneration and necrosis,which were visible in the red pulp necrosis,and bleeding,splenic sinus blood volume,edema were observed in spleen.For liver,local inflammation occurs in tissues with serous material infiltration,and a large number of eosinophilic cells can be seen in the space with congestion and bleeding.In addition,encyst was found in nucleated cells.By means of observing kidney,the study found that its degeneration,necrosis,congestion and bleeding,edema,and there are many eosinophils can be seen in the kidney gap.