改性蜡质玉米淀粉稳定Pickering乳液的制备及应用

Preparation and application of Pickering emulsion stabilized by modified waxy maize starch

采用辛烯基琥珀酸酐(OSA)对蜡质玉米淀粉(WS)疏水改性制得辛烯基琥珀酸酐改性蜡质玉米淀粉(OSA-WS),以不同取代度OSA-WS制备了稳定的Pickering乳液。测定了OSA-WS取代度(DS)、反应效率(RE)及三相接触角,对其进行了FT-IR、XRD和SEM表征。结果表明,OSA通过与淀粉表面羟基反应对其进行改性并未改变淀粉颗粒结构;随着取代度的增大,淀粉颗粒乳化性增加,制得Pickering乳液稳定性增强;以OSA-WS为乳化剂制得包埋辅酶Q10的Pickering乳液,通过透皮运输实验可知,与辅酶Q10的油溶液相比,包埋辅酶Q10的Pickering乳液更有利于辅酶Q10的透皮运输。

The waxy maize starch （WS） was hydrophobically modified by octenyl succinic anhydride （OSA） to prepare the modified waxy maize starch (OSA - WS）. Stable Pickering emulsions were prepared by using OSA - WS with different degree of substitution （DS）. The DS, reaction efficiency (RE) and three - phase contact angle of OSA - WS were measured. The OSA - WS was characterized by FT - IR, XRD and SEM. The results show that, by reacting with the hydroxyl groups on the surface of starch, OSA has been successfully grafted without changing the granule of starch. The emulsifying ability of OSA - WS becomes stronger with larger DS, thus the storage stability of Pickering emulsion is also increased with DS. The Pickering emulsion emulsified by OSA - WS was then applied in the transdermal transport of coenzyme Q10. Compared with the oil solution of coenzyme Q10, the Pickering emulsion containing coenzyme Q10 is more favorable for transdermal transport of eoenzyme Q10.