无精子症患者生育压力对生活质量的影响及相关性研究

Impact of infertility-related psychological stress on the quality of life of azoospermia patients

目的:研究无精子症患者生育压力与生活质量的现状,探讨无精子症患者生育压力对其生活质量的影响及相互关系。方法:采用FPI量表和Feti Q0L量表对我院2017年1月至2017年7月经门诊诊断为无精子症、需经睾丸穿刺活检明确病因的503例无精子症患者进行横断面调查,描述无精子症生育压力与生活质量的现状,评价其生育压力、生活质量,探讨无精子症生育压力与生活质量的相互关系。结果:无精子症患者生育压力综合得分为(153.60±27.21)分,生活质量总得分(64.22±14.68)分,多重线性回归结果显示:无精子症患者生活质量的重要影响因素为生育压力、文化程度、年龄等(β=-0.298、-0.093、0.099,P<0.05);Pearson相关分析结果显示无精子症患者生育压力的各个维度与其生活质量总分均呈负相关(P<0.01)。结论:生育压力是无精子症患者生活质量重要的影响因素;且生育压力越大,生活质量越差;应重视无精子症给患者造成的心理压力,并制定积极有效的干预措施,进而提高无精子症患者的生活质量。

Objective： To investigate the impact of infertility-related psychological stress(IRPS） on the quality of life(QOL）of azoospermia patients and the correlation between IRPS and QOL. Methods： Using the Fertility Problem Inventory and Fertility-Related QOL(Ferti QOL） questionnaire,we carried out a cross-sectional study among 503 azoospermia patients treated in our center from January to July 2017,all subjected to testicular biopsy for identification of the causes. We analyzed the IRPS and QOL of the patients and explored their correlation. Results： The total score of the azoospermia patients for IRPS was 153. 60 ± 27. 21 and that for QOL was 64. 22 ± 14. 68. Multivariate linear regression analysis showed that the main factors influencing the patients＇ QOL included IRPS(β =-0. 298,P〈0. 05）,education(β =-0. 093,P〈0. 05）,and age(β = 0. 099,P〈0. 05）. Pearson correlation analysis revealed a negative correlation of the total QOL score with all the factors for IRPS(P〈0. 01）. Conclusion： IRPS is an important factor affecting azoospermia patients＇ QOL,the higher the IRPS,the worse the QOL. Therefore,sufficient attention and effective intervention measures are needed for the improvement of their QOL.