瑜伽运动对乳腺癌患者负性情绪及生活质量影响的meta分析

Effects of yoga on negative emotions and quality of life in patients with breast cancer: a meta-analysis

目的系统评价瑜伽运动对乳腺癌患者负性情绪及生活质量的改善作用。方法计算机检索PubMed、Wiley、The Cochrane Library、Science Direct、CNKI、CBM、万方数据库、维普数据库中关于瑜伽运动改善乳腺癌患者负性情绪及生活质量的随机对照研究,筛选相关文献,并对纳入文献进行质量评价和资料提取,采用Rev Man 5.2软件进行meta分析。结果共纳入7篇文献,其中干预组共330例患者,对照组共341例患者。Meta分析显示,瑜伽运动可以改善乳腺癌患者的焦虑症状(SMD=-0.47,95%CI-0.83～-0.10,P=0.01),减轻抑郁症状(SMD=-0.63,95%CI-0.82～-0.43,P<0.01),提高生活质量(MD=10.36,95%CI 5.80～14.93,P<0.01),缓解癌性疲劳,但在改善乳腺癌患者的睡眠质量方面并未显示出明显优势。结论瑜伽运动可以缓解乳腺癌患者的负性情绪,提高生活质量,但在改善睡眠质量方面无明显优势。

Objective To assess the effect of yoga on negative emotions and quality of life in patients with breast cancer. Method We searched the PubMed, Wiley, The Cochrane Library, Science Direct, CNKI, CBM, Wanfang and VIP database to collect all randomized controlled Trials （RCTs） regarding yoga intervention in patients with breast cancer. Two researchers independently select the literature and make quality assessment. Meta-analysis was used with Rev Man 5.2. Result 7 studies were included. The result showed that yoga can improve the level of anxiety symptom[SMD=-0.47,95%CI（-0.83,-0.10）,P=0.01],depression symptom[SMD=-0.63,95%CI（-0.82,-0.43）,P〈0.001]and quality of life[MD=10.36,95%CI（5.80,14.93）,P〈0.001]and relieve the cancer-related fatigue.However,yoga has no significance related with improving quality of sleep in breast cancer patients. Conclusion Yoga can relieve negative emotions and improve the quality of life in breast cancer patients, and there was no obvious advantage in terms of sleep quality, a large-scale randomized controlled trial was conducted.