摘要
目的:回顾性调查小儿风湿免疫科住院患者超说明书用药情况,为规范儿科用药提供依据。方法:随机抽取吉林大学第一医院2014年9月-2015年9月小儿风湿免疫科300例住院患者病历,根据药品说明书判断是否为超说明书用药,并对超说明书用药的数量及类型分别进行统计分析。结果:随机抽取的300例住院患者超说明书用药发生率为96%。其中,用药医嘱超说明书用药发生率28.79%;涉及药品212种,超说明书用药发生率44.81%。超说明书用药类型以超适应人群(78.21%)所占比例最大。结论:我院小儿风湿免疫科存在超说明书用药现象,应加强超说明书用药的规范管理,促进儿科安全合理用药。
Objective: To retrospectively analyze the off-label drug use by inpatients in Pediatric Rheumatology and Immunology Department of the First Hospital of Jilin University and to provide references for rational drug use. Methods: The medical records of 300 inpatients in this hospital from September 2014 to September 2015 were randomly selected. The off-label drug use was judged according to package inserts. Moreover, the number and kinds of off-label drug use were statistically analyzed. Results: The incidence of off-label drug in 300 inpatients was 96%, among which 28.79% was prescription off-label drug use involving 212 kinds of drugs(accounting for 44.81%). Over-appropriate population had the highest incidence(accounting for 78.21%). Conclusion: Off-label drug use existed in Pediatric Rheumatology and Immunology Department of our hospital. We should strengthen standard management of off-label drug use and promote safe and rational drug use.
作者
于雪娇
张四喜
宋燕青
Yu Xuejiao;Zhang Sixi;Song Yanqing(The First Hospital of Jilin University, Changchun 130021, China)
出处
《中国药事》
CAS
2018年第5期682-686,共5页
Chinese Pharmaceutical Affairs
关键词
超说明书用药
小儿风湿免疫
规范用药
off-label drug use
Pediatric Rheumatology and Immunology
rational drug use