克咳片辅助治疗慢性阻塞性肺疾病临床疗效观察

Clinical effect of basic treatment combined with Keke Tablets on Chronic obstructive pulmonary disease

目的探讨基础治疗联合克咳片治疗慢性阻塞性肺疾病的临床疗效。方法选取本病患者共60例,随机分为试验组和对照组各30例,试验组采用基础治疗+克咳片治疗,对照组采用基础治疗,疗程为1个月,每周随访1次。比较治疗前后组内和组间m MRC和CAT的差异,评估患者治疗前后咳痰、咳嗽、气短评分变化及治疗前后组内组间FEV1%差异。结果与治疗前比较,两组治疗后m MRC评分及CAT评分显著降低,差异有统计学意义(P<0.05);两组治疗后组间比较,差异无统计学意义,但试验组治疗前与治疗后的差值大于对照组。单项症状疗效分析结果显示,两组治疗后咳嗽、咳痰、气短疗效评分均较治疗前明显减少,差异有统计学意义(P<0.05);试验组与对照组治疗后咳嗽、咳痰组间比较,差异有统计学意义(P<0.05)。FEV1%疗效分析结果显示,试验组与对照组治疗前后组内比较,FEV1%均明显改善,差异有统计学意义(P<0.05);两组治疗后组间比较,差异无统计学意义,但试验组治疗前后的差值大于对照组。结论克咳片联合基础用药治疗慢性阻塞性肺疾病有较好的疗效,尤其是在改善患者咳嗽、咳痰方面,疗效确切。

Objective To study the clinical curative effect of 60 cases of basic treatment combined with Keke Tablets on Chronic obstructive pulmonary disease. Method A total of 60 patients were selected, who were randomly divided into treatment group and control group （30 cases/group）. Treatment group： basic treatment and Keke Tablets, control group： basic treatment. Result Keke with the curative effect of mMRC, CAT and FEVI% with Tablets and basic drug treating COPD, there was no statistical difference. The treatment group was better than control group in individual symptoms of cough and sputum. Conclusion Keke Tablets combined with basic drugs in the treatment of chronic obstructive pulmonary disease has better curative effect, especially in improving cough and expectoration, the curative effect is exact.