不同批次四川栽培白芍药材的质量分析研究

Quality analysis of cultivated Paeoniae Radix Alba in Sichuan

目的:通过对不同批次四川渠县栽培白芍进行薄层、水分、总灰分、浸出物、重金属及有害元素(铅、砷、汞、铜、铬)检验,及芍药苷含量测定,以评价药材质量。方法:选取10批次四川渠县栽培白芍药材,参照2015年版《中国药典》一部项下检验方法,对其主要指标成分芍药苷的含量,以及薄层、水分、总灰分、浸出物、重金属及有害元素(铅、砷、汞、铜、铬)等检查项进行检验。结果:白芍样品中芍药苷的含量为3.67±0.45%,水分的含量为12.78±0.82%,总灰分的含量为2.93±0.52%,浸出物的含量为24.32±1.96%,均在标准范围内,且重金属含量均低于其限量值。结论:四川栽培白芍中芍药苷含量,以及薄层、水分、总灰分、浸出物、重金属及有害元素(铅、砷、汞、铜、铬)等检查项均符合2015年版《中国药典》规定,质量合格。

Objective：To evaluate the quality of different batches of cultivated Paeoniae Radix Alba in Sichuan by thin layer chromatography and investigating moisture,total ash,extract,the heavy metals and harmful elements.Method：The quality control methods of Chinese Pharmacopeias（2015） were used to test the contents of paeoniflorin,moisture,total ash,extract,the heavy metals and harmful elements（lead,arsenic,mercury,copper and chromium） in 10 batches of samples.Result：The contents of paeoniflorin,moisture,total ash,extract in samples were 3.67±0.45%,12.78±0.82%,2.93±0.52%,24.32±1.96%,respectively,which were in the standard range And the heavy metals and harmful elements contents were lower than the limits prescribed in pharmacopoeia.Conclusion：All the quality inspection items of Paeoniae Radix Alba cultivated in Sichuan conform to the standards in Pharmacopeias of China（2015）.The results show the quality of cultivated paeoniae Radix Alba in Sichuan is good.