摘要
生物体是天然活性蛋白质的宝库,近年来,越来越多具有生物活性的蛋白质被发现和研究,在生物制药、营养食品等方面具有广阔的应用前景。然而,分离纯化的技术与策略将影响天然蛋白的活性与功能,以及相关的经济效益。基于目前研究现状,对生物活性蛋白质的分离纯化技术进行了综述。
Biosome is the most ideal sources of naturally bioactive proteins.In recent years,more and more bioactive proteins have been found and studied,and these proteins have a bright future in the application of biopharmaceuticals and functional foods.However,the techniques and strategies of separation and purification processes have an important impact on the activities,functions,as well as economic benefits of bioactive proteins.The advances in separation and purification of bioactive proteins are reviewed based on the current researches and reports.
作者
王金秋
陈加传
李柯萌
谭昕
肖静
刘纯友
WANG Jinqiu;CHEN Jiachuan;LI Kemeng;TAN Xin;XIAO Jing;LIU Chunyou(Key Laboratory of Coarse Cereal Processing (Ministry of Agriculture), College of Pharmacy and Bioengineering, Chengdu University (Chengdu 610106;Key Laboratory of Green Processing of Guangxi Sugar Resources, School of Biological and Chemical Engineering, Guangxi University of Science and Technology (Liuzhou 545006)
出处
《食品工业》
CAS
北大核心
2018年第5期259-263,共5页
The Food Industry
基金
国家自然科学基金(31701655)
四川省教育厅科研项目(17ZA0080)
成都大学校青年基金(2080517042)
关键词
生物活性蛋白质
分离
纯化
双水相萃取
混合型色谱
bioactive proteins
separation
purification
aqueous two-phase extraction
mixed-mode chromatography