摘要
A conjugated 8-hydroxyquinoline( 8-HQ)-based fluorescent chemosensor( 1) for Zinc ion( Zn^(2+)) and Cadmium ion( Cd^(2+)) was developed in aqueous solution and used for Zinc ion living cells bioimaging. The probe 1 was weakly fluorescent,but displayed a strong fluorescence at 580 nm with a large Stokes shift of150 nm in the presence of Zn^(2+) or Cd^(2+). This probe allows the detections of Zn^(2+) in the range of 0. 8-10 μmol/L and Cd^(2+) in the range of 0. 8-8 μmol/L,with the limit of detections of 0. 2 and 0. 6μmol/L for Zn^(2+) and Cd^(2+),respectively. The present probe was successfully used for fluorescence bioimaging of Zn^(2+) or Cd^(2+) in the living cells.
A conjugated 8-hydroxyquinoline（ 8-HQ）-based fluorescent chemosensor（ 1） for Zinc ion（ Zn^（2＋）） and Cadmium ion（ Cd^（2＋）） was developed in aqueous solution and used for Zinc ion living cells bioimaging. The probe 1 was weakly fluorescent,but displayed a strong fluorescence at 580 nm with a large Stokes shift of150 nm in the presence of Zn^（2＋） or Cd^（2＋）. This probe allows the detections of Zn^（2＋） in the range of 0. 8-10 μmol/L and Cd^（2＋） in the range of 0. 8-8 μmol/L,with the limit of detections of 0. 2 and 0. 6μmol/L for Zn^（2＋） and Cd^（2＋）,respectively. The present probe was successfully used for fluorescence bioimaging of Zn^（2＋） or Cd^（2＋） in the living cells.
基金
Shanghai Municipal Natural Science Foundation,China(No.16ZR1401700)
