海洋藻类藻胆蛋白的提取、纯化与应用研究进展

Advances in extraction,purification and application of phycobiliprotein from marine algae

藻胆蛋白(phycobiliprotein,PBP)是一种具备多种生物活性的藻类捕光色素蛋白,其既可作为功能因子与天然色素应用于食品、保健品、药品和化妆品等领域,又可作为光敏剂与荧光探针应用于生物医学领域,具有良好的应用前景。作为一种优质的胞内蛋白,藻胆蛋白的提取富集通常包括破壁、粗提和纯化三个步骤。本文重点介绍了海洋藻类藻胆蛋白的提取和分离纯化的新型工艺,并讨论了其在天然色素、保健食品与医药、荧光探针和光敏剂的应用研究进展,以期为海洋藻类的高值化加工和应用提供重要参考。

Phycobiliprotein （PBP）is a kind of algae chromoprotein with a variety of biological activities.The application prospect of phyeobiliprotein is also good.It not only can be used as a functional factor and natural pigment in food, health care products, pharmaceuticals and cosmetics ,but also can be used as a photosensitizer and fluorescent probe in the field of biomedicine.As a high quality intracellular protein, the extraction and enrichment of phycobiliprotein usually involves the following steps： crushing, separation and purification.This paper focused on study of new technology on extraction, separation and purification of marine algae phycobiliproteins and discussed its application in natural pigments, health care food and medicine, fluorescent probes and photosensitizers research progress, which provided important reference for the high value processing and application of marine algae.