摘要
目的分析梅毒螺旋体抗体(TP-Ab)金标试纸在无偿献血初筛中的应用价值。方法选择青岛市中心血站2014年1月-2017年10月采集的183 429份全血为研究对象,选择其中TP阳性样本50份及阴性样本1 000份,采用TP-Ab金标试纸复检。结果初筛梅毒螺旋体(TP)阳性率分别为0.79%、0.73%、0.65%、0.66%,合计阳性率为0.71%。复查TP阳性率分别为0.48%、0.39%、0.21%、0.27%,合计0.34%。TP-Ab金标试纸法的灵敏度为70.0%、特异度为99.9%、阳性预测值为97.2%、阴性预测值为98.5%,符合率为98.5%。结论 TP-Ab金标试纸作为无偿献血梅毒感染的初筛方法效果较好,能够有效降低复查梅毒阳性率,值得临床推广。
Objective To analyze the application value of Treponema Pallidum Antibody(TP-Ab) Gold Standard Test Paper in the initial screening of free blood donation. Methods 183 429 whole blood samples collected from Qingdao city center blood station in January 2014 to October 2017 were selected as the research object. 50 TP positive samples and 1 000 negative samples were selected. Reexamination by TP-Ab Gold Standard Test Paper were given to them. Results The treponema pallidum(TP) positive rate of initial screening were 0.79%,0.73%,0.65%,0.66%,and the total positive rate was 0.71%. The TP positive rate of reexamination were 0.48%,0.39%,0.21%,0.27%,and the total positive rate was 0.34%. The sensitivity of TP-Ab Gold Standard Test Paper was 70.0%,specificity was 99.9%,positive predictive value was 97.2%,negative predictive value was 98.5%,and the coincidence rate was 98.5%. Conclusion The TP-Ab Gold Standard Test Paper is a good screening method for the syphilis infection of initial screening of free blood donation,and it can effectively reduce the positive rate of reexamination of syphilis. It is worth popularizing.
作者
成枫
CHENG Feng(Department of Blood Donation Service, Qingdao City Center Blood Station, Qingdao Shandong Province 266071, China)
出处
《中国城乡企业卫生》
2018年第5期3-5,共3页
Chinese Journal of Urban and Rural Enterprise Hygiene
关键词
无偿献血
梅毒螺旋体抗体金标试纸
初筛
Free blood donation
Treponema Pallidum Antibody Gold Standard Test Paper
Initial screening