喜疗妥治疗吡柔比星所致40例化疗性静脉炎的临床观察

Clinical observation on Hirudoid treating pirarubicin induced chemotherapeutic phlebitis:a report of 40 cases

目的观察喜疗妥治疗吡柔比星所致化疗性静脉炎的临床效果。方法将80例乳腺癌化疗中使用浅表静脉留置针静滴吡柔比星所致的化疗性静脉炎的患者随机分为实验组和对照组各40例,实验组采取拔除留置针后予患处外涂喜疗妥软膏。对照组采取拔除留置针后予50%硫酸镁溶液湿敷患处。观察两种方法的临床效果。结果实验组治疗总有效率(97.5%)明显优于对照组(77.5%),(P<0.05);实验组用药后的红肿消退时间以及疼痛缓解时间均明显短于对照组,(P<0.05)。结论使用喜疗妥软膏外涂治疗吡柔比星所致的化疗性静脉炎的效果良好,在短时间内能有效地解除局部红肿和缓解疼痛,并且患者使用方便,值得在基层医院广泛应用。

Objective To observe the clinical effect of treating pirarubicin induced phlebitis by Hirudoid. Methods 80 cases of breast cancer patients suffered from chemotherapeutic phlebitis were randomly divided into experimental group and control group,40 cases in each group. The chemotherapeutic phlebitis was induced by superficial venous indwelling needle drops of pirarubicin during the chemotherapy. Patients in experiment group were given pirarubicin at the wounded part,while patients in the control group were given magnesium sulphuricum solution（ 50%） soaking,and observed the clinical efficacy of the two methods.Results Total effective rate of patients in the experimental group（ 97.5%） was better than control group（ 77.5%）,P〈0.05. Swelling subsided time and pain relief time in the experimental group was significantly shorter than patients in the control group,P〈0.05.Conclusions The effect of Hirudoid in treating pirarubicin induced chemotherapeutic phlebitis is well,it can effectively relieve swelling and pain in a short period and it＇s easy to use.It is worthy to be widely used in clinical practice.