针刺对脑—心卒中患者血中内皮素、一氧化氮含量影响的动态观察

Dynamic Observation on Effects of Acupuncture on Blood Endothelin and Nitric Oxide Levels in the Patient of Cerebro-Cardiac Apoplexy

目的:探讨针刺治疗急性脑卒中引发心脏损伤的机制,观察不同腧穴组方的疗效差异。方法:将100例急性脑卒中引发心脏损伤患者随机分为2组,针刺现察组50例,针刺对照组50例。观察治疗前、后2周急性脑卒中引发心脏损伤患者血浆ET、血清NO含量的变化。结果:急性脑卒中引发心脏损伤患者血浆ET、血清NO含量显著高于健康对照组。针刺观察组治疗1周、2周后,血浆ET、血清NO含量明显降低,其改善程度明显优于对照组。结论:针刺可良性调整急性脑卒中引发心脏损伤患者血中ET、NO水平,维持神经内分泌体液平衡,保护受损心肌,并且不同的选穴组方,其疗效有显著的差异。

Purpose To probe into the mechanism of acupuncture for treatment of cardiac injuries induced by acute cerebral apoplexy and observe on differences of therapeutic effects of different prescriptions of acupoint. Methods 100 cases of cardiac injuries induced by acute cerebral apoplexy were randomly divided into two groups, acupuncture observation group and control group, 50 cases in each group. Their plasma endothelin (ET) and serum nitric oxide levels were investigated before the treatment and 2 weeks after the treatment. Results The ET and NO levels in the patient of cardiac injuries induced by acute cerebral apoplexy were significantly higher than that in the healthy control group; the ET and NO levels in the acupuncture observation group one week, two weeks after the treatment decreased significantly and the improving extent was significantly superior to that of the control group. Conclusion Acupuncture can optimally regulate blood ET and NO levels in the patient of cardial lesion induced by cerebral apoplexy to protect injuried myocardium, and different prescriptions of acupoint have significantly different therapeutic effects.