摘要
对1株具有抗芒果炭疽病菌活性的海口湾海泥来源放线菌Streptomyces sp.HNWSW-49发酵液的化学成分进行研究。采用多种色谱技术对化合物进行分离纯化,以波谱数据确定化合物的结构。从来源于海口湾海泥的放线菌Streptomyces sp.HNWSW-49发酵液的乙酸乙酯提取物中分离鉴定了7个含氮化合物,分别为:环-(苯丙-丙)二肽(1),环-(亮-甘)二肽(2),环-(苯丙-缬)二肽(3),环-(羟脯-苯丙)二肽(4),N-(2-苯基)乙酰胺(5),β-腺苷(6),和2-哌啶酮(7)。所有化合物均为首次从该放线菌中分离得到,其中化合物6为首次从微生物中分离得到。
The chemical constituents from the fermentation broth of Streptomyces sp. HNWSW-49, which was isolated from the sediment of Haikou Bay and showed anti-fungal activity against Colletotrichum gloeosporioides in postharvest Mango, was studied. Seven compounds were isolated with various chromatographic techniques. Meanwhile, the structures of the compounds were identified through a combined analysis of physicochemical properties and spectroscopic evidence. They were determined as ascyclo-（Phe-Ala）（1）, cyclo-（Leu-Gly）（2）, cyclo-（Phe-Val）（3）, cyclo-4-OH-Pro-Phe（4）, N-（2-phenylethyl） acetamide（5）, β-Adenosine（6）, and 2-Piperidone（7）. The compounds were obtained from the Streptomyces sp. HNWSW-49 for the first time, while 6 was the first time isolated from microorganisms.
作者
吉才娟
王佩
梅文莉
黄小龙
戴好富
JI Caijuan;WANG Pei;MEI Wenli;HUANG Xiaolong;DAI Haofu(Institute of Tropical Agriculture and Forestry Hainan University, Haikou, Hainan 570228, China;Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan 571101, China)
出处
《热带作物学报》
CSCD
北大核心
2018年第4期758-762,共5页
Chinese Journal of Tropical Crops
基金
海南省自然科学基金面上项目(No.20163117)
国家自然科学基金青年科学基金项目(No.41506096)
关键词
海泥
放线菌
化学成分
含氮化合物
marine sediment
Streptomyces sp.
chemical constituents
nitrogenous compounds
