摘要
目的评价生物羊膜移植在复杂眼表疾病及眼表重建手术中的临床疗效。方法回顾分析2011年1月至2016年12月行生物羊膜移植手术的复杂眼表疾病74例(74眼)的临床资料。结果其中复发性翼状胬肉25眼(33.78%)、角膜溃疡20眼(27.03%)、化学伤15眼(20.27%)、睑球粘连10眼(13.51%)、持续性角膜上皮缺损2眼(2.70%)、眼睑基底细胞癌1眼(1.35%)、Stevens—Johnson综合征1眼(1.35%)。随访6~24个月后再手术12眼(16.22%),包括翼状胬肉复发3眼(3/25,12.00%),角膜溃疡2眼(2/20,10.00%),化学伤4眼(4/15,26.67%),睑球粘连2眼(2/10,20.00%),Stevens—Johnson综合征1眼(1/1,100.00%)。所有患者术后均未出现感染、移植排斥或过敏反应。结论生物羊膜移植是治疗复杂眼表疾病的有效方法。
Objective To evaluate the clinical efficacy of biological amniotic membrane transplantation in complicated ocular surface disease and ocular surface reconstruction. Methods The data of 74 eyes of 74 patients with complicated ocular surface disease from Jan. 2011 to Dec. 2016 were analyzed retrospectively. They underwent biological amniotic membrane transplantation. Results The most common primary diseases was recurrent pterygium in 25 eyes (33.78%), followed by corneal ulcer in 20 eyes (27.03%), chemical injury in 15 eyes (20.27%), symblepharon in 10 eyes (13. 51%), persistent epithelial defects (PED) in 2 eyes (2.70%), eyelid basal cell carcinoma in 1 eye (1.35%) and Stevens-Johnson syndrome (SJS) in 1 eye (1.35%). After 6-24 months follow-up, there were 12 eyes (16.22%) reoperated, including pterygium recurrence in 3 eyes (3/25,12.00%) , corneal ulcer in 2 eyes (2/20, 10.00%) , chemical injury in 4 eyes (4/15,26.67%) , symblepharon in 2 eyes (2/10,20.00%) , SJS 1 in eye (1/1, 100. 00%). No infection, graft Conclusion Amniotic membrane transplantation ocular surface diseases rejection or allergic reaction after surgery occurred. is an effective method for the treatment of complicated
作者
聂爱芹
李强
李伟
Nie Aiqin;Li Qiang;Li Wei(Department of Ophthalmology, Shenzhen People' s Hospital, The Second Clinical Medical College of Ji ' nan University, Shenzhen 518020, China)
出处
《中华眼外伤职业眼病杂志》
2018年第5期348-351,共4页
Chinese Journal of Ocular Trauma and Occupational Eye Disease
关键词
移植
生物羊膜
疾病
眼表
翼状胬肉
溃疡
角膜
化学伤
Transplantation
biological amniotic membrane
Diseases
ocular surface
Pterygium
Ulcer
corneal
Injury
chemical