临床药师对肝衰竭患者使用维生素K_1治疗的药学监护

Pharmaceutical Care for One Patient with Liver Failure Treated with Vitamin K_1 by Clinical Pharmacists

目的:探讨临床药师对肝衰竭患者使用维生素K_1治疗的药学监护模式及内容,促进临床合理用药。方法:临床药师参与1例慢加急肝衰竭患者治疗过程,结合患者病情,对治疗方案的选择和临床疗效实施药学监护,通过循证证据分析肝衰竭患者持续使用维生素K_1的合理性。结果:对于维生素K_1治疗无效的肝衰竭患者,不建议继续使用维生素K_1。结论:维生素K_1在肝衰竭患者中的应用应慎重,应在临床有确切证据提示维生素K缺乏的情况下合理使用,以确保用药安全。

OBJECTIVE： To probe into the model and content of pharmaceutical care for the patient with liver failure treated with vitamin K1, so as to promote the rational drug use in clinic. METHODS： Combined with the patients＇ conditions, the clinical pharmacists participated into the treatment process of one patient with liver failure, provided pharmaceutical care for the selection of treatment regimen and clinical efficacy, and analyzed the rationality of using vitamin K1 through the evidence-based evidence. RESULTS： If vitamin K1 was an ineffective treatment for patients with liver failure, vitamin K1 was not recommended. CONCLUSIONS： It is necessary to attach more importance to the use of vitamin Kl in patient with liver failure. Proper use should be given in the case of clinical evidence of vitamin K deficiency, which can ensure the medication safety and rationality.