膝骨性关节炎病变因素与小针刀疗法疗效的相关性

Correlation Analysis between Different Disease Factors of Knee Osteoarthritis and Efficacy of the Small Needle Knife Therapy

目的:评价小针刀疗法治疗膝骨性关节炎的临床疗效和不同病变因素与疗效的相关性。方法:选取2011年1月至2011年9月新疆医科大学附属中医医院收治的符合膝骨性关节炎诊断标准的患者200例,所有患者均对病变程度进行评价后并采用小针刀进行治疗,治疗结束后4周、8周对比疗效,将不同病变特征与治疗结果行Logistic回归分析。结果:脱落及失访病例5例,余195例患者均得到随访。针刀治疗后4周、8周总有效率分别为95.2%、96.1%,与治疗前比较,差异有统计学意义(P<0.05);影像学分级、间室病变个数、病程长短、体重、关节畸形程度等属影响疗效的独立危险因素。结论:小针刀疗法治疗膝骨性关节炎临床疗效肯定,但应根据患者的病变程度,合理选择治疗方法,从而为患者制定个性化的针刀治疗措施。

Objective： To verify the clinical efficacy of small needle knife therapy in the treatment of knee osteoarthritis,and to analyze the correlation between different pathological factors and efficacy. Methods： A total of 200 cases of patients with knee osteoarthritis who were admitted and treated in our hospital from January 2011 to September 2011 were selected. All the patients were evaluated for the degree of pathological changes and treated by small needle knife therapy. The curative effect was compared four weeks and eight weeks after treatment. The logistic regression analysis was conducted for different pathological characteristics and treatment results. Results： There were 5 cases of shedding and loss to follow-up. The other 195 patients were followed up after the small needle knife treatment. The total effective rates were 95. 2% and 96. 1% four weeks and eight weeks after treatment,which was statistical significant when compared with before treatment（ P〈 0. 05）. Logistic regression analysis showed that the radiographic classification,number of interventricular lesions,course of disease,weight,joint deformity were the independent risk factors that affected clinical efficacy,namely the above factors were becoming worse,and the clinical efficacy became invalid. Conclusion： Small needle knife therapy in the treatment of knee osteoarthritis has certain efficacy,but proper treatment should be selected based on the severity of each patient,so as to develop personalized needle knife therapy for patients.