UAE介入治疗对子宫肌瘤患者临床疗效的影响

Effect of UAE interventional therapy on clinical efficacy of patients with hysteromyoma

目的探讨子宫动脉栓塞术(VAE)介入治疗对不同数量子宫肌瘤患者临床症状、并发症及肌瘤体积和钙化的影响。方法选取2015年1月至2017年6月杭州市余杭区第一人民医院收治的71例子宫肌瘤患者,根据其子宫肌瘤数量分组,单发子宫肌瘤者为对照组35例,多发子宫肌瘤者为研究组36例,对比分析两组临床症状、并发症及肌瘤体积和钙化影响。结果两组月经量增多、经期延长、直肠压迫、尿路压迫等临床症状缓解率均无显著性差异(χ~2值分别为3.55、2.46、3.85、3.99,均P>0.05);两组发热、恶心、呕吐等术后并发症发生率均无明显差异(均P>0.05);对照组和研究组肌瘤体积较术前均显著缩小(t值分别为11.38、21.20,均P<0.01),肌瘤钙化率较术前均显著升高(χ~2值分别为8.12、13.49,均P<0.01),且研究组肌瘤钙化率(86.67%)明显高于对照组(53.33%)(χ~2=10.53,P<0.01)。结论子宫动脉栓塞术介入治疗对不同数量子宫肌瘤患者均存在较佳的治疗效果,且两组疗效相当,临床上值得进一步应用和推广。

Objective To investigate the effects of uterine artery embolization （UAE） interventional therapy on the clinical symptoms, complications, fibroid volume and calcification of patients with hysteromyoma of different number. Methods Seventy one cases of hysteromyoma were selected in People＇s Hospital in Yuhang District, and 35 cases with single hysteromyoma were assigned to control group and 36 cases with multiple hysteromyoma to study group. Clinical symptoms, complications, fibroids volume and calcification were compared between two groups. Results The improvement rate of increased menstrual flow, menostaxis, rectum oppression, urinary tract oppression and other clinical symptoms between two groups showed no significant difference （χ2 value was 3.55, 2.46, 3.85 and 3.99, respectively, all P〉0.05）. The incidence rate of fever, nausea, vomiting and other complications between two groups showed no significant difference （all P〉0.05）. The fibroid volume in both groups was significantly smaller than that before surgery （t value was 11.38 and 21.20, respectively, both P〈0.01）, and the calcification rate was higher （χ2 value was 8.12 and 13.49, respectively, both P〈0.01） and the calcification rate in the study group （86.67% ） was higher than that in the control group （53.33%） （χ2= 10.53, P〈0.01）. Conclusion The UAE interventional therapy on patients with different number of hysteromyoma has better clinical efficacy, and the efficacy of two groups is similar, which is worthy of further clinical application and promotiorL