遗传性泛发性色素异常症伴副银屑病1例

A Case of Dyschromatosis Universalis Hereditaria with Parapsoriasis

患者男,35岁。反复四肢、躯干丘疹、红斑、鳞屑伴瘙痒5年,加重1年。体查时发现患者及家族中3代,6人均自幼即出现全身皮肤泛发性色素沉着伴色素减退或色素脱失斑,无自觉症状。根据患者的临床表现及两种皮损的组织病理学特征,诊断为遗传性泛发性色素异常症伴副银屑病。

A 35-year-old male presented with repeated symptoms pimples,erythema,scales with itching on his limbs and trunk for 5 years,which aggravated for over 1 year. Physical examination and family history found that patients and members of three generations of his family,six persons appeared in infancy the body skin generalized pigmentation with hypomelanosis or pigment deprivation,no symptoms. According to the clinical manifestations of patients and pathologic features of two lesions of the organization,the diagnosis was dyschromatosis universalis hereditaria with parapsoriasis.