类风湿关节炎与高脂饮食、肠道菌群的关系研究进展

Research progress on the relationship between rheumatoid arthritis and high-fat diet and intestinal microbiota

类风湿关节炎是一种以慢性关节炎症为主要表现的全身自身免疫性疾病,其发病受众多因素的影响,有待进一步明确。许多研究发现,高脂饮食可能通过诱发肠道菌群失调,进而参与类风湿关节炎发病。本文仅对高脂饮食及肠道菌群失调与类风湿关节炎的发病关系进行相关综述,以期为类风湿性关节炎的防治提供新的策略。

Rheumatoid arthritis is a systemic autoimmune disease characterized by chronic joint inflammation.Its incidence is affected by many factors, which need to be further clarified. Many studies have found that high-fat diet may lead to the onset of rheumatoid arthritis by inducing intestinal dysbacteriosis. This article reviews the pathogenesis of high-fat diet and intestinal dysbacteriosis and rheumatoid arthritis, with a view to providing new strategies for the prevention and treatment of rheumatoid arthritis.