孟鲁司特钠在儿科门诊应用的调查分析

Investigation and Analysis of Montelukast Sodium Application in Pediatric Outpatients

目的:分析孟鲁司特钠在我院门诊患者中的使用情况及处方合理性。方法:对2016年7-9月我院门诊含孟鲁司特钠的处方(共8 499份)中不同孟鲁司特钠剂型和规格在总的处方中出现的频次及频率进行统计并对其用法用量的合理性进行分析。结果:在含有孟鲁司特钠的处方中,颗粒剂4 mg、咀嚼片4 mg及咀嚼片5 mg出现频次分别为6 589、984及928次,频率为77.5%、11.6%及10.9%。按常规用法用量,颗粒剂4 mg、咀嚼片4 mg及咀嚼片5 mg出现频次分别6 458、966及920次,合格率达到98.01%、98.37%及99.14%。特别用法用量的处方出现155频次,占总处方的1.89%。根据患儿年龄选择合适的剂型剂量,不适宜的达1 586次(18.44%),颗粒剂4 mg、咀嚼片4 mg及咀嚼片5 mg出现不合格的频次分别为1 295、269及22次。结论:我院门诊孟鲁司特钠的临床使用基本合理,其中特别需要注意区分患儿年龄,为患儿的治疗选择更合理更合适的剂型剂量。

Objective： To analyze the application and prescribing rationality of montelukast sodium in outpatients from our hospital. Methods： Prescriptions containing montelukast sodium （8 499 in total） were statistically summarized and analyzed from July to Sept. 2016, in terms of the frequency and frequency of different montelukast formulations and specifications in the total prescriptions and the rationality of the usage and dosage. Results： In the formulation containing montelukast sodium, granules 4 rag, chewable tablets 4 mg and chewable tablets 5 mg were presented 6 589,984 and 928 times. The proportions were respectively 77.5% , 11.6% and 10.9%. According to conventional usage and dosage, the frequency of granules 4 mg, chewable tablets 4 mg and chewable tablets 5 mg were presented 6 458, 966 and 920 times, respectively. The qualified rates were respectively 98.01%, 98. 37% and 99. 14%. Special prescription was prescribed 155 times by usage and dosage, 1.89% share in total prescriptions. Incorrect prescription share was l 586 times （18.44%） according to patients＇ corresponding age. The unqualified frequency of granules 4 mg, chewable tablets 4 mg and chewable tablets 5 mg were presented 1 295, 269 and 22 times. Conclusion： The application of montelukast sodium in our hospital is basically reasonable. Clinical application should pay more attention to the children＇ s age and choose the more appropriate dosage for the treatment of children.