信宜市食管癌高发区居民食管癌及癌前病变状况分析

Analysis of the Condition of Esophageal Carcinoma and Precancerous Lesion in the High Incidence of Esophageal Cancer in Xinyi City

目的:了解信宜市食管癌高发区居民食管癌及癌前病变的分布情况,为食管癌的防治工作提供依据。方法:在信宜市食管癌高发区2011年1月至2016年1月采取随机抽样的方法选择居民820例为对象,采取内镜下碘染色及指示性活检进行检测,并由一般理论医学知识进行诊断。结果:研究共收集筛查居民820例,其中发现食管癌36例,早期癌2例,癌前病变14例,食管中度异型增生38例,食管炎症共86例,食管轻度异型增生42例,男性中度异型增生和重度异性增生/原位癌的检出率高于女性,差异有统计学意义(P<0.05)。分布在50～65岁的各级食管病变高于其他组。结论:在信宜市食管癌高发区人群中存在着相当数量的癌前病变患者,应做好知识宣传,加强预防。

Objective To understand the distribution of esophageal cancer and precancerous lesions in patients with esophageal cancer in xiny.i city, and provide a basis for the prevention and treatment of esophageal cancer. Methods Esophageal cancer high incidence in Guangdong province Xinyi city, cluster random sampling method to select part of the population from Jan.2011 to Jan.2016 a total of 820 cases of object,as a screening of high - risk groups to take iodine staining under endoscopy and indicative biopsy, screening and the pathological basis for diagnosis. Results Study collected screening residents 820 cases,of which found esophageal inflammation,a total of 86 patients,esophageal mild hyperplasia 42 cases,moderate esophagus hyperplasia 38 cases of precancerous lesions（severe hyperplasia/esophagus carcinoma in situ）, 14 cases of early carcinoma 2 cases, 36 cases with esophageal carcinoma, and the detection rate of male moderate dysplasia and severe heterosexual hyperplasia / carcinoma in situ was higher than that in females, with a statistically significant difference （P 〈 0.05）. Conclusion There are a large number of patients with precancerous lesions in the high incidence area of esophageal cancer in Xinyi City, and knowledge propaganda should be done to strengthen prevention.