脑卒中后新发房颤对其复发的影响

Effect of atrial fibrillation after stroke on stroke recurrence

目的探讨脑卒中后新发房颤对其复发的影响。方法选择2014-01—2016-01郑州人民医院收治的脑卒中患者148例,通过Kaplan-Meier生存统计脑卒中复发率,通过Cox风险比例分析房颤发生与脑卒中复发的相关性。结果 4.5%的患者首次诊断为房颤,14.2%的患者出现脑卒中复发;Kaplan-Meier分析显示,新发房颤患者中脑卒中的复发率为19.1%;相关性分析显示,新发房颤与复发脑卒中风险比(HR)为5.8,95%CI 3.5~9.8。结论脑卒中患者新发房颤与脑卒中复发显著相关,亦见于既往有房颤史的患者,对其关系的研究有利于评估脑卒中患者的复发风险。

Objective To explore the effect of atrial fibrillation（AF）on the recurrence of stroke after stroke in patients with stroke.Methods A total of 148 patients with stroke were selected from January 2014 to January 2016.All patients were followed up after discharge and the risk of stroke recurrence was measured by Kaplan-Meier survival.Mortality and stroke were analyzed by Cox risk ratio analysis the relevance.Results 4.5% of patients were diagnosed with atrial fibrillation for the first time and 14.2%had recurrent stroke.One year after discharge,Kaplan-Meier analysis showed that the recurrence rate of stroke in patients with newly developed AF was 19.1%.The correlation analysis showed that the risk ratio of new onset AF and recurrent stroke was5.8,95% confidence interval（CI）3.5-9.8.Conclusion Patients with stroke are significantly associated with recurrent episodes of atrial fibrillation and stroke recurrence,which were also seen in patients with previous history of atrial fibrillation.It is beneficial to assess the risk of recurrence in patients with stroke.