摘要
整合药理学(integrative pharmacology,IP)是研究多成分药物与机体相互作用及其整合规律和作用原理的一门学科,强调"整体与局部"、"体内与体外"、"体内过程与活性评价"等多层次、多环节的整合研究。经过4年的发展与实践,整合药理学的理论与方法得到了广泛的关注与应用。为了促进该学科更好、更快发展,该文从概念、研究内容、研究方法、应用领域等方面进行系统综述。
Integrative pharmacology( IP) is a discipline that studies the interaction,integration and principle of action of multiple components with the body,emphasizing the integrations of multi-level and multi-link,such as " whole and part", " in vivo and in vitro", " in vivo process and activity evaluation". After four years of development and practice,the theory and method of IP has received extensive attention and application. In order to better promote the development of IP,this paper systematically reviews the concepts,research contents,research methods and application fields about IP.
作者
王萍
唐仕欢
苏瑾
张佳琪
崔如意
许海玉
杨洪军
WANG Ping;TANG Shi-huan;SU Jin;ZHANG Jia-qi;CUI Ru-yi;XU Hai-yu;YANG Hong-jun(Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China;Chinmedomics Research Center of State Administration of Traditional Chinese Medicine, Heilongjiang University of Chinese Medicine, Harbin 150040, China)
出处
《中国中药杂志》
CAS
CSCD
北大核心
2018年第7期1297-1302,共6页
China Journal of Chinese Materia Medica
基金
国家自然科学基金面上项目(81473414,81473584,81774201)
国家科技支撑计划项目(2011BAI07B08)
关键词
中药方剂
整合药理学
药效物质基础
活性评价
traditional Chinese medicine prescription
integrative pharmacology
pharmacodynamic material basis
activity evaluation