从久病入络论述特发性肺纤维化合并支气管扩张

Analysis on Idiopathic Pulmonary Fibrosis Combined with Bronchiectasis from Prolonged Illness Invading Collaterals

特发性肺纤维化合并支气管扩张在间质性肺疾病发展过程中越来越常见,为多种慢性肺系疾病后期发展而成,由气到血、由功能性病变到器质性病变的病理演变,后期多伴有痰浊、血瘀而致肺络瘀阻,肺叶枯萎,与“久病入络”观点不谋而合。高分辨率CT表现为双侧和下底肺为主,胸膜下分布的网状影或蜂窝影。活血化瘀、解毒通络是基本治疗原则,从“久病入络”之络病学基本概念、特发性肺纤维化和支气管扩张的中西医临床研究现状论述特发性肺纤维化合并支气管扩张的机制、发展特点。

Idiopathic pulmonary fibrosis（IPF） combined with bronchiectasis are becoming more and more common in the development of interstitial lung disease,which are developed from various chronic and advanced pulmonary diseases,evolving from qi to blood,from functional changes to organic pathologic changes, accompanied with turbid phlegm and blood stasis obstructing lung collateral causing withering of lung col- lateral. High-resolution CT shows bilateral and lower lung-based,subpleural distribution of mesh shadow or honeycomb. Activating blood and resolving stasis,detoxing and dredging collaterals are the basic treatment principles. ＂Prolonged illness invading the coUaterals＂,current situations of clinical research of traditional Chinese and western medicine on IPF and bronchiectasis discusses the mechanism and features of IPF combined with bronchiectasis to provide the theoretical basis for clinical therapy.