强迫症患者元认知、强迫症状和生活质量的关系

Metacognitive Beliefs,Obsessive-compulsive Symptoms and Quality of Life of Patients with Obsessive-compulsive Disorder

目的：探讨强迫症患者元认知、强迫症状和生活质量的关系。方法：对符合DSM-5诊断标准的55例强迫症患者以及性别、年龄相匹配的正常对照组67名,采用元认知问卷（MCQ-30）、耶鲁布朗强迫量表（YBOCS）和生活质量量表（WHOQOL）进行测量。结果：强迫症患者在除了担忧的积极信念外,元认知总分及各因子得分、耶鲁布朗总分及各因子得分上均显著高于正常对照组（t=3.937-24.673,P〈0.01）,而生活质量得分显著低于正常对照组（t=-8.774,P〈0.01）。强迫症患者耶鲁布朗总分与生活质量呈显著负相关（r=-0.376,P〈0.05）;回归分析表明,认知自信、不可控和危险性的消极信念对生活质量有负向作用。结论：强迫症患者的元认知、症状严重程度和生活质量密切相关,其中认知自信、不可控和危险性的消极信念对生活质量有负向作用。

Objective：To explore the relationship among metacognitive beliefs,obsessive-compulsive symptoms and quality of life of patients with obsessive-compulsive disorder（OCD）.Methods：A total of 55 patients with obsessive-compulsive disorder as diagnosized in accordance with the Diagnostic and Statistical Manual of Mental Disorders（the Fifth Edition）（DSM-V）were chosen to form an experiment group,and 67 gender-and age-matched adults were chosen to form a control group.Metacognitions Questionnaire-30（MCQ-30）,Yale-Brown Obsessive– Compulsive Scale（Y-BOCS）and World Health Organization Questionnaire on Quality of Life（WHOQOL）were utilized for the assessment.Results：The experiment group scored higher than the control group in MCQ total and domain scores,Y-BOCS total and domain scores,except for positive beliefs about worry（t=3.937~24.673,P 0.01）,the experiment group scored lower than the control group in total WHOQOL score（t=-8.774,P〈0.01）;Total Y-BOCS score was negatively correlated with the quality of life of patients with OCD（r=-0.376,P〈0.05）;Stepwise regression analysis revealed that the cognitive confidence and negative beliefs about uncontrollability and danger had negative effect on the quality of life of the patients with OCD.Conclusion：Metacognition beliefs,obsessive-compulsive symptoms are significantly correlated with the quality of life.The cognitive confidence and negative beliefs about uncontrollability and danger have negative effects on the quality of life of the patients with OCD.