颅内静脉窦血栓形成的主要特点及诊治策略

The main characteristic and treatment strategy of cerebral venous sinus thrombosis

目的探讨颅内静脉窦血栓形成(cerebral venous sinus thrombosis,CVST)的主要特点及诊治。方法对我院收治的14例CVST患者进行回顾性分析。结果 CVST是一种少见的脑血管疾病,通常以中青年多见,往往急性起病,临床表现主要有颅高压症状或者局灶性神经功能缺损,如头痛、头晕、恶心、呕吐,癫痫、偏瘫等。早期使用抗凝治疗是取得良好预后的关键。结论 CVST临床表现复杂多样,利用MRV、CTV或DSA发现静脉窦狭窄、闭塞是确诊CVST的关键之一;有助于临床工作的要做到早期诊断和规范有效治疗。

Objective To investigate the clinical characteristics,imaging features and diagnosis and treatment strategies of cerebral venous sinus thrombosis（ CVST）. Methods The clinical data on fourteen cases of CVST patients treated in our hospital was retrospectively analyzed. Results CVST was a rare cerebrovascular disease to which the young and middle-aged were most vulnerable,with an acute or subacute onset. The majority of patients had clinical manifestations of intracranial hypertension or focal brain damage,such as headache,dizziness,nausea,vomiting,seizures and hemiplegia. The diagnosis of CVST depends on imaging features. Early use of anticoagulant therapy was effective. Conclusions The clinical manifestations of CVST are variable. MRV or DSA will contribute to early diagnosis. Early diagnosis and effective treatment are important to the outcome.