孕产妇脓毒症的流行病学及预防策略

Epidemiology of maternal sepsis and prevention strategies

脓毒症是全球孕产妇发病和死亡的重要原因,影响到母婴结局,危害大。有别于成人脓毒症,目前孕产妇脓毒症的定义和诊断标准尚不精确,可能导致诊治的延误;病原学也经历着变迁。对其认识的提高、早期识别和及时治疗是控制其发病率增长、改善预后的关键。本文从发生、定义、诊断标准、病原学、感染源以及管理和防控等多角度对孕产妇脓毒症进行阐述,旨在提高大家对于孕产妇脓毒症的进一步认识,有利于实践及防控。

As a leading cause of maternal morbidity and mortality worldwide,sepsis is harmful and may influence the pregnancy outcome.However,being different from sepsis in adults,the maternal sepsis is not defined accurately at present and the diagnostic criteria are not yet precise,which may lead to delays of diagnosis and treatment.Etiology has also experienced change.Increased awareness,early identification and timely treatment are crucial to the control of increase of morbidity rate and improvement of prognosis.The maternal sepsis was elaborated by multidimensional review of incidence,definition,diagnostic criteria,etiology and source of infection as well as prevention and management so as to raise the awareness of the disease and facilitate the practice and prevention.