针灸治疗原发性失眠常用选穴处方优化研究

Research on the Common Acupoints Formulation Optimization about Acupuncture Treatment of Pprimary Insomnia

目的:通过本研究对针刺治疗原发性失眠常用选穴处方进行优化,初步拟定针刺治疗原发性失眠的基础方。方法:采用随机对照研究方法将90例原发性失眠症患者随机分为针刺1组、针刺2组,西药对照组,每组30例,治疗4周,应用匹兹堡睡眠质量量表(PSQI)评定临床疗效。结果:治疗1、2周后,三组PSQI量表总分比较,差异均具有统计学意义(P<0.05);治疗4周后,针刺1组与西药对照组经统计学分析,P=0.220(P>0.05),差异无统计学意义,针刺2组与另两组比较P<0.05,差异具有统计学意义。针刺1组总有效率89.29%;针刺2组总有效率93.10%,西药对照组总有效率为86.21%,P=0.751,但三组差异没有统计学意义(P>0.05)。结论:针灸治疗原发性失眠具有较好疗效,与西药对照组疗效相当甚至优于西药对照组,尤其在远期疗效和安全性方面,而且针刺2组疗效优于针刺1组,其处方可作为针灸治疗原发性失眠的基础选穴处方。

Objective： According to the research to optimize common acupoints formulation,drafted the basic prescription of acupuncture treatment of primary insomnia. Methods： Using a randomized complete control study,the collected 90 patients with primary insomnia were divided into acupuncture group 1,acupuncture group 2,Western medicine controlled group,30 cases each,treatment for 4 weeks. Clinical efficacy was assessed by the Pittsburgh sleep quality scale（ PSQI）. Results： After 1 and2 weeks,comparison of the three groups of PSQI scale score,the difference was statistically significant（ P〈0. 05）. After 4 weeks of treatment,the acupuncture group 1 and the western medicine controlled group by statistical analysis,P = 0. 220（ P 〈0. 05）,the difference was not statistically significant. The acupuncture group 2 and the other two groups（ P 〈0. 05）,the difference was statistically significant. The total effective rate was 89. 29% in the acupuncture group 1 and the total effective rate in the acupuncture group 2 was 93. 10%,the total effective rate in the western medicine group was 86. 21%,（ P = 0. 751）,but the difference between the three groups was not statistically significant（ P〉0. 05）. Conclusion： Acupuncture has good curative effect on insomnia compared with the western medicine controlled group,even the curative effect is better than it,especially in the long-term efficacy and safety. And the effect of acupuncture group 2 was better than that acupuncture group 1,the prescription can be used as the basic of acupuncture treatment for insomnia.