加减杞菊地黄汤联合复方樟柳碱对眼底病患者血流动力学及视觉功能影响

Effects of Modified Qiju Dihuang Decoction Combined with Anisodine on Hemodynamics and Visual Function in Patients with Eyesight Disease

目的：探究加减杞菊地黄汤联合复方樟柳碱对眼底病患者血流动力学及视觉功能的影响。方法：选取2015年1月—2016年4月收治的84例眼底病患者作为研究对象,运用随机数字表法将其分为观察组（杞菊地黄汤联合复方樟柳碱）、对照1组（杞菊地黄汤组）、对照2组（复方樟柳碱）,每组28例。比较3组的疗效、治疗前后血液流变学变化、复发情况及不良反应等。结果：观察组患者中治疗总有效率为96.43%,对照1组患者治疗总有效率为75.00%,对照2组患者治疗总有效率为71.43%;两对照组无明显差异（P〉0.05）,观察组与两对照组比较均具有明显差异（均P〈0.05）,3组患者经相应治疗后血液流变学浓度均有明显下降（P〈0.05）,且观察组的效果较为明显,与两个对照组比较均有明显差异（均P〈0.05）;观察组的复发情况明显少于两对照组,差异均具有统计学意义（P〈0.05）。观察组与两对照组进行比较,观察组患者的不良反应较少,与两对照组比较具有明显差异（P〈0.05）。结论：加减杞菊地黄汤联合复方樟柳碱对眼底病患者血流动力学及视觉功能的治疗效果明显优于单一使用杞菊地黄汤或复方樟柳碱,患者血液流变学浓度下降更为明显,不良反应较少,预后效果更佳,值得临床推广应用。

Objective：To study the effects of Qiju Dihuang Decoction combined with compound anisodine on blood flow in patients with fundus disease dynamics and visual function. Methods：From January 2015 to April 2016 84 cases of fundus disease patients in our hospital as the research object,using a random number table method divided into the observation group（Qiju Dihuang Decoction combined with compound anisodine）,control group 1（Qiju Dihuang Decoction group）,control group 2（compound anisodine）,28 cases in each group. The curative effect was compared between the three groups,the changes of hemorrheology before and after treatment,recurrence and adverse reactions. Results：The patients in the observation group of the total effective rate was 96.43%. According to the control group 1 of patients the total effective rate was 75.00%,control group 2 of patients treated with total effective rate was 71.43%;two control group had no significant difference（P〉0.05）,the observation group and two control group were compared with significant difference（P〈0.05）,three groups of patients after the treatment of blood rheology were decreased significantly（P〈0.05）,and the effect of the observation group is more obvious,with two control group had significant difference（P〈0.05）;the observation group recurrence rate was less than two in control group,the differences were statistically significant（P〈0.05）. The observation group and two control group for comparison,observation the group of patients with less adverse reactions,with significant difference with two control group（P〈0.05）. Conclusion：The curative effect of the treatment effect of Qiju Dihuang Decoction combined with compound anisodine on blood flow in patients with fundus disease dynamics and visual function is superior to the single use of Qiju Dihuang Decoction or compound anisodine,hemorheology concentration decreased more obviously,less adverse reaction,better prognosis,worthy of clinical application.