从痰瘀互结论治冠心病的研究进展

Research progress on the treatment of coronary heart disease based on the theory of intermin-gled phlegm and blood stasis

冠心病是冠状动脉发生粥样硬化性病变而引起血管腔狭窄或阻塞,造成心肌缺血、缺氧或坏死而导致的心脏病,具有较高的病死率。动脉粥样硬化及心肌缺血作为冠心病的基础病理特征,更容易导致痰瘀等病理因素的形成,目前痰瘀互结证发病率高,病变程度严重,逐渐受到重视。文章通过大量文献研究,从发病机制、临床表现、现代研究、药物治疗4个方面作一综述,为临床上痰瘀同治治疗冠心病提供更多的思路方法及理论依据。

Coronary artery disease is a kind of heart disease caused by coronary atherosclerotic lesions with high mortality, which may cause myocardial ischemia, hypoxia and necrosis. As the basic pathological characteristics of coronary heart disease, atherosclerosis and myocardial ischemia are more likely to lead to the formation of pathological factors, such as phlegm and blood stasis. At present, the incidence of syndrome of intermin-gled phlegm and blood stasis is high and the severity of the disease is serious. This paper mainly reviewed the progress on the treatment of coronary artery disease with syndrome of intermingled phlegm and blood stasis from the prospective of pathogenesis, clinical manifestations, modern research and drug treatment, to provide more ideas and theoretical basis for clinical treatment of coronary artery disease.