药对淫羊藿-白芍治疗老年腰椎间盘突出症的临床研究

Clinical study on medicine suits of Epimedium Herb and Radix Paeoniae Alba in treating elderly patients with lumbar disc heriation

目的:观察中药药对淫羊藿-白芍对老年腰椎间盘突出症(LDH)患者的临床疗效。方法:收集2013年1月至2015年9月就诊于中国医学科学院西苑医院及中国中医科学院望京医院且年龄≥65岁的LDH患者,共81例,分为中医治疗组42例(仅予中药口服)和西医对照组39例(仅予扶他林治疗),评价其疼痛NRS评分以及总体疗效。结果:(1)疼痛NRS评分:治疗前两组NRS评分差异无统计学意义,治疗后中医治疗组评分(2.81±1.43)较西医对照组(4.01±1.41)显著降低(P<0.05)。(2)总体疗效:中医治疗组总有效率是95.24%,西医对照组总有效率是89.74%,中医治疗组疗效优于西医对照组(P<0.05)。结论:药对淫羊藿-白芍在改善老年LDH症状体征积分及缓解疼痛方面具有优势,值得进一步研究及推广。

Objective： To observe the clinical efficacy of medicine suits of Epimedium Herb and Radix Paeoniae Alba in the treatment of senile lumbar disc herniation（LDH）. Methods： From January 2013 to September 2015, a total of 81 LDH patients older than 65 years old in Xiyuan Hospital of Chinese Academy of Medical Sciences and Wangjing Hospital of China Academy of Traditional Chinese Medicine were divided into Chinese medicine treatment group（42 cases, only oral Chinese medicine） and western medicine control group（39 cases, only treated with Voltaren）. The pain NRS score and total physical therapy were evaluated. Results：（1）Pain NRS score： there was no significant difference in the NRS score between the two groups before treatment, and the score of the TCM treatment group was 2.81＋1.43 after treatment, which was lower than the western medicine control group（4.01＋1.41）（P〈0.05）.（2）The total effective rate of the Chinese medicine treatment group was 95.24%, the total effective rate of the western medicine control group was 89.74%, and the curative effect of the Chinese medicine treatment group was effective. Compared with the western medicine control group, the difference was statistically significant（P〈0.05）. Conclusion： Medicine suits of Epimedium Herb and Radix Paeoniae Alba have advantages in improving symptoms and signs integral and alleviating pain in elderly patients with prolapse of lumbar intervertebral disc. It is worth further research and promotion.