获得性多发性斑状毛细血管扩张八例临床特征分析

Clinical analysis of eight patients with telangiectasia macularis multipiex acquisita

回顾性分析8例获得性多发性斑状毛细血管扩张(TMMA)的临床特征。8例患者全部为男性,平均年龄48.2岁。皮损分布于双上肢、前胸、背后,均表现为大小不等的红斑间杂散在斑状毛细血管扩张,遇热或饮酒、摩擦后皮疹加重。组织病理基本上无特异性,8例甲苯胺蓝染色均阴性。5例误诊为持久性斑疹性毛细血管扩张,2例误诊为毛细血管扩张型环状紫癜,1例误诊为硬皮病。皮损予喜疗妥、丁苯羟酸乳膏、他克莫司或吡美莫司乳膏均无疗效。

The data of 8 male patients with telangiectasia macularis multipiex acquisita（ TMMA） was retrospectively analyzed. The average age was 48. 2 years. All the patients presented with expanded capillary among erythemas on the double upper limbs,chest and back. The lesions can get worse after friction and drinking. There was no specificity of histopathology and toluidine blue stain was negative in all patients. Five patients were misdiagnosis as telangiectasia macularis eruptive acquisita,two as capillary dilated purpura and one as scleroderma. The treatment with hirudoid,butylphenyl hydroxylate cream,tacrolimus or pimimox cream was ineffective.