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细胞型朊蛋白(PrP^C)在消化道恶性肿瘤中的表达及其临床意义 被引量:2

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摘要 肿瘤的发生发展、侵袭转移都是由多种基因、多个蛋白信号转导通路调控及多步骤协同发生的生物学过程,近年来消化道恶性肿瘤发病率有逐渐上升趋势,且死亡人数增加,因此,寻找新的消化系统肿瘤标志物以及控制恶性肿瘤的恶化及转移,对其早期发现、诊断、治疗及预后判断有重要意义。近几年的研究表明细胞型朊蛋白对癌症细胞的生长、爬行和抗药性都有作用,提示细胞型朊蛋白可能与恶性肿瘤的发生、发展、侵袭以及转移等有着密切的关系。
出处 《实用癌症杂志》 2018年第6期1037-1039,共3页 The Practical Journal of Cancer
基金 江西省科技厅支撑计划(编号:20142BBG70082) 江西省卫生和计划生育委员会科技计划(编号:20155518)
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