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分子吸附再循环系统应用时机与方法 被引量:1

Application timing and methods of molecular adsorbent recirculating system
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摘要 分子吸附再循环系统(molecular adsorbent recirculating system)是一种新型人工肝脏支持系统,由血液循环、白蛋白再生循环和透析循环回路组成,主要替代肝脏解毒功能,清除内源性和外源性毒素,同时调节水电解质和酸碱平衡,改善内环境。促进肝细胞再生。可用于急性肝衰竭、慢加急性肝衰竭和中毒等的支持治疗,为肝脏功能得以恢复争取时间或肝移植提供桥梁的作用。 Molecular adsorbent recirculating system is a new artificial liver support system. It consists of blood circulation, albumin regeneration cycle and dialysis circulation circuites. It mainly replaces liver de- toxification function, removes endogenous and exogenous toxins, and regulates water and electrolyte and acid- base balance. The internal environment promotes hepatocyte regeneration. It can be used in the treatment of a- cute liver failure, acute-on-chronic liver failure, and poisoning. Molecular adsorbent recirculating system pro- vides time for recovery of liver function or a bridge for liver transplantation.
作者 曾健生 Zeng Jiansheng(National Children's Medical Center. Pediatric Intensive Care Unit, Beijing Children's Hospital, Capital Medical University ,Beijing 100045, Chin)
出处 《中国小儿急救医学》 CAS 2018年第5期330-334,共5页 Chinese Pediatric Emergency Medicine
关键词 白蛋白透析 分子吸附再循环系统 肝衰竭 Albumin dialysis Molecular adsorbent recirculating system Liver failure
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  • 1周新民,苗继延,杨艳,赵琳,王新,徐立,吴开春,丁杰,樊代明.MARS人工肝治疗急慢性肝功能衰竭48例临床分析[J].透析与人工器官,2004,15(2):10-15. 被引量:12
  • 2Mitzner SR, Stange J, Klammt S, et al. Extracorporeal detoxification using the molecular adsorbents recirculating system for critically ill patients with liver failure. J Am Soc Nephrol, 2001, 12(Suppl 17): S75-S82.
  • 3Stange J, Hassanein TI, Mehta R, et al. The molecular adsorbents recycling system as a liver support system based on albumin dialysis:a summary of preclinical investigations, prospective, randomized,controlled clinical trial, and clinical experience from 19 centers.Artif Organs. 2002, 26:103-110.
  • 4Schmidt LE, Sorensen VR, Svendsen LB, et al. Hemodynamic changes during a single treatment with the molecular adsorbents recirculating system in patients with acute-on-chronic liver failure. Liver transpl,2001, 7: 1034-1039.
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