卡贝缩宫素在剖宫产术中应用效果观察

Application effect of Carbetocin during cesarean section

目的研究观察卡贝缩宫素在剖宫产术中术后的应用效果。方法以我院在2014年6月-2016年6月期间收治的134例行剖宫产手术的产妇为研究对象,按随机数字表法均分为观察组和对照组,观察组患者术中给予卡贝缩宫素进行治疗,而对照组患者术中给予缩宫素进行常规治疗。比较两组患者应用后的对子宫的缩宫效果、术中及术后的出血量以及用药后出现的不良反应比较。结果观察组患者子宫程度显著高于对照组(P<0.05);观察组术中及术后各时间点的平均出血量、产后出血率均低于对照组(P<0.05);观察组不良反应发生率显著低于对照组(P<0.05)。结论卡贝缩宫素的有着较高的缩宫效果,能够降低术中和术后出血量,安全性高,疗效显著,可在临床上进一步推广使用。

Objective To investigate the effect of carbetocin during and after cesarean section surgery. Methods 134 cases being treated with cesarean section surgery in our hospital from June 2014 to June 2016 were chosen as the research objects. All case were randomly divided into observation group and control group. Observation group were given carbetocin during surgery, while the patients in the control group were given conventional treatment of oxytocin. Uterine contraction effect, hemostatic effect, intraoperative and postoperative bleeding volume and adverse drug reactions were compared between two groups. Results Uterine contraction effect and hemostatic effect were significantly higher than those in the control group（P〈0.05）;, The average amount of bleeding in each time point during operation and after operation in observation group were lower than those in control group（P〈0.05）; The incidence rate of adverse reactions was significantly lower than that in the control group（P〈0.05）. Conclusion Carbetocin have better effect and it can reduce the amount of bleeding during and after operation with high safety, efficacy. It can be further used in clinical practice.