期刊文献+

超小剂量地西他滨治疗慢性粒单核细胞白血病1例 被引量:2

A case of chronic myelomonocytic leukemia treated with ultra low dose of decitabine
原文传递
导出
摘要 1病例资料患者,女,73岁,2016年8月无明显诱因下出现头晕乏力、纳差,时有中上腹不适,伴有呕吐胃内容物,反酸,入住我院消化科。入院体检:全身皮肤黏膜无黄染、无出血点,浅表淋巴结未及肿大,胸骨无压痛,心肺无异常,肝脾肋下未及。8月26日查血常规提示:白细胞6.2×109/L,单核细胞1.0×109/L,红细胞2.95×1012/L,血红蛋白94g/L,血小板132×109/L。 This article introduced a case of old woman with chronic myelomonocytic leukemia treated by decitabine regimen(10 mg,d1 to d3)per course every two weeks.After four courses of treatment,the patient achieved complete remission.Then we summarized the successful experience.
出处 《临床血液学杂志》 CAS 2018年第3期383-384,共2页 Journal of Clinical Hematology
基金 上海市宝山区中西医结合医院科研资助项目(No:201601) 宝山区卫生青年医学人才培养计划资助项目(No:bswsyq-2016-A11) 上海市卫生和计划生育委员会科研课题(No:201640144)
关键词 慢性粒单核细胞白血病 超小剂量 地西他滨 chronic myelomonocytic leukemia ultra low dose decitabine
  • 相关文献

参考文献2

二级参考文献11

  • 1IASTREBNER M,JANG J H,NUCIFORA E,et al.Decitabine in myelodysplastic syndromes and chronic myelomonocytic leukemia:Argentinian/South Korean multi-institutional clinical experience[J].Leuk Lym-phoma,2010,51:2250-2257.
  • 2JABBOUR E,GARCIA-MANERO G,BATTY N,et al.Outcome of patients with myelodysplastic syn-drome after failure of decitabine therapy[J].Cancer,2010,116:3830-3834.
  • 3GERMING U,KUNDGEN A,GATTERMANN N.Risk assessment in chronic myelomonocytic leuke-mia[J].Leuk Lymphoma,2004,45:1311-1318.
  • 4OKI Y,JELINEK J,SHEN L,et al.Induction of hy-pomethylation and molecular response after decitabine therapy in patients with chronic myelomonocytic leu-kemia[J].Blood,2008,111:2382-2384.
  • 5CHESON B D,GREENBERG P L,BENNETT J M,et al.Clinical application and proposal for modification of the International Working Group(IWG)response criteria in myelodysplasia[J].Blood,2006,108:419-425.
  • 6VALENT P,HORNY H P,BENNETT J M,et al.Definitions and standards in the diagnosis and treat-ment of the myelodysplastic syndromes:Consensus statements and report from a working conference[J].Leuk Res,2007,31:727-736.
  • 7ARIBI A,BORTHAKUR G,RAVANDI F,et al.Ac-tivity of decitabine,a hypomethylating agent,in chro-nic myelomonocytic leukemia[J].Cancer,2007,109:713-717.
  • 8WIJERMANS P W,RUTER B,BAER M R,et al.Ef-ficacy of decitabine in the treatment of patients with chronic myelomonocytic leukemia[J].Leuk Res,2008,32:587-591.
  • 9KANTARJIAN H,OKI Y,GARCIA-MANERO G,et al.Results of a randomized study of3schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia[J].Blood,2007,109:52-57.
  • 10中华医学会血液学分会.骨髓增生异常综合征诊断与治疗中国专家共识(2014年版)[J].中华血液学杂志,2014,35(11):1042-1048. 被引量:208

共引文献10

同被引文献16

引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部